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However, its efficacy is significantly limited by DNA repair mechanisms, particularly the activity of MGMT, which reverses guanine methylation and reduces TMZ-induced cytotoxicity

Recovery The numbing effect usually lasts a few hours after the injection

Additionally, YYT targets and AS-related proteins formed 3,732 protein-protein interaction (PPI) pairs, highlighting two key targets: JAK2 and signal transducer and activator of transcription 3 (STAT3)

Zhou N, Rice D, Corsini E, Antonoff M, Hofstetter W, Rajaram R, Roth J, Swisher S , Vaporciyan A, Walsh GL, Mehran R, Sepesi B

Both Mn@mHSA and Mn/TI@mHSA exhibited nearly identical oxygen generation as Mn 3 O 4 NPs at equivalent Mn concentrations, indicating their comparable CAT-like activities